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Investigation of binding behaviour of procainamide hydrochloride with human serum albumin using synchronous, 3D fluorescence and circular dichroism

Interaction of procainamide hydrochloride (PAH) with human serum albumin (HSA) is of great significance in understanding the pharmacokinetic and pharmacodynamic mechanisms of the drug. Multi-spectroscopic techniques were used to investigate the binding mode of PAH to HSA and results revealed the pre...

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Detalles Bibliográficos
Autores principales: Byadagi, Kirthi, Meti, Manjunath, Nandibewoor, Sharanappa, Chimatadar, Shivamurti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686859/
https://www.ncbi.nlm.nih.gov/pubmed/29404024
http://dx.doi.org/10.1016/j.jpha.2016.07.004