Stability study on an anti-cancer drug 4-(3,5-bis(2-chlorobenzylidene)-4-oxo-piperidine-1-yl)-4-oxo-2-butenoic acid (CLEFMA) using a stability-indicating HPLC method

CLEFMA, 4-(3,5-bis(2-chlorobenzylidene)-4-oxo-piperidine-1-yl)-4-oxo-2-butenoic acid, is a new chemical entity with anti-cancer and anti-inflammatory activities. Here, we report its stability in solution against stress conditions of exposure to acid/base, light, oxidant, high temperature, and plasma...

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Detalles Bibliográficos
Autores principales: Raghuvanshi, Dhawal, Nkepang, Gregory, Hussain, Alamdar, Yari, Hooman, Awasthi, Vibhudutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686864/
https://www.ncbi.nlm.nih.gov/pubmed/29404012
http://dx.doi.org/10.1016/j.jpha.2016.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686864/
https://www.ncbi.nlm.nih.gov/pubmed/29404012
http://dx.doi.org/10.1016/j.jpha.2016.09.004

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