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Simultaneous analysis of allopurinol and oxypurinol using a validated liquid chromatography–tandem mass spectrometry method in human plasma

The present study describes a simple, reliable and reproducible liquid chromatography–tandem mass spectrometry method (LC–MS/MS) for the simultaneous determination of allopurinol and its active metabolite, oxypurinol in human plasma for a pharmacokinetic/bioequivalence study. After protein precipita...

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Detalles Bibliográficos
Autores principales: Rathod, Dhiraj M., Patel, Keyur R., Mistri, Hiren N., Jangid, Arvind G., Shrivastav, Pranav S., Sanyal, Mallika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686867/
https://www.ncbi.nlm.nih.gov/pubmed/29404018
http://dx.doi.org/10.1016/j.jpha.2016.05.005