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Cefepime-induced neurotoxicity: a systematic review

BACKGROUND: Cefepime is a widely used antibiotic with neurotoxicity attributed to its ability to cross the blood–brain barrier and exhibit concentration-dependent ϒ-aminobutyric acid (GABA) antagonism. Neurotoxic symptoms include depressed consciousness, encephalopathy, aphasia, myoclonus, seizures,...

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Detalles Bibliográficos
Autores principales: Payne, Lauren E., Gagnon, David J., Riker, Richard R., Seder, David B., Glisic, Elizabeth K., Morris, Jane G., Fraser, Gilles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686900/
https://www.ncbi.nlm.nih.gov/pubmed/29137682
http://dx.doi.org/10.1186/s13054-017-1856-1