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Cefepime-induced neurotoxicity: a systematic review
BACKGROUND: Cefepime is a widely used antibiotic with neurotoxicity attributed to its ability to cross the blood–brain barrier and exhibit concentration-dependent ϒ-aminobutyric acid (GABA) antagonism. Neurotoxic symptoms include depressed consciousness, encephalopathy, aphasia, myoclonus, seizures,...
Autores principales: | Payne, Lauren E., Gagnon, David J., Riker, Richard R., Seder, David B., Glisic, Elizabeth K., Morris, Jane G., Fraser, Gilles L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686900/ https://www.ncbi.nlm.nih.gov/pubmed/29137682 http://dx.doi.org/10.1186/s13054-017-1856-1 |
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