Synthetic oleanane triterpenoids enhance blood brain barrier integrity and improve survival in experimental cerebral malaria

BACKGROUND: Cerebral malaria (CM) is a severe complication of Plasmodium falciparum infection associated with high mortality and neurocognitive impairment in survivors. New anti-malarials and host-based adjunctive therapy may improve clinical outcome in CM. Synthetic oleanane triterpenoid (SO) compo...

Descripción completa

Detalles Bibliográficos
Autores principales: Crowley, Valerie M., Ayi, Kodjo, Lu, Ziyue, Liby, Karen T., Sporn, Michael, Kain, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686938/
https://www.ncbi.nlm.nih.gov/pubmed/29137631
http://dx.doi.org/10.1186/s12936-017-2109-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686938/
https://www.ncbi.nlm.nih.gov/pubmed/29137631
http://dx.doi.org/10.1186/s12936-017-2109-0

Ejemplares similares