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Synthetic oleanane triterpenoids enhance blood brain barrier integrity and improve survival in experimental cerebral malaria

BACKGROUND: Cerebral malaria (CM) is a severe complication of Plasmodium falciparum infection associated with high mortality and neurocognitive impairment in survivors. New anti-malarials and host-based adjunctive therapy may improve clinical outcome in CM. Synthetic oleanane triterpenoid (SO) compo...

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Detalles Bibliográficos
Autores principales:	Crowley, Valerie M., Ayi, Kodjo, Lu, Ziyue, Liby, Karen T., Sporn, Michael, Kain, Kevin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686938/ https://www.ncbi.nlm.nih.gov/pubmed/29137631 http://dx.doi.org/10.1186/s12936-017-2109-0

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