The balance between Gα(i)-Cdc42/Rac and Gα(1)(2)/(1)(3)-RhoA pathways determines endothelial barrier regulation by sphingosine-1-phosphate

The bioactive sphingosine-1-phosphatephosphate (S1P) is present in plasma, bound to carrier proteins, and involved in many physiological processes, including angiogenesis, inflammatory responses, and vascular stabilization. S1P can bind to several G-protein–coupled receptors (GPCRs) activating a num...

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Detalles Bibliográficos
Autores principales: Reinhard, Nathalie R., Mastop, Marieke, Yin, Taofei, Wu, Yi, Bosma, Esmeralda K., Gadella, Theodorus W. J., Goedhart, Joachim, Hordijk, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687037/
https://www.ncbi.nlm.nih.gov/pubmed/28954861
http://dx.doi.org/10.1091/mbc.E17-03-0136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687037/
https://www.ncbi.nlm.nih.gov/pubmed/28954861
http://dx.doi.org/10.1091/mbc.E17-03-0136

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