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The FcεRI signaling cascade and integrin trafficking converge at patterned ligand surfaces

We examined the spatial targeting of early and downstream signaling mediated by the immunoglobulin E (IgE) receptor (FcεRI) in RBL mast cells using surface-patterned 2,4-dinitrophenyl (DNP) ligands. Micron-sized features of DNP are presented as densely immobilized conjugates of bovine serum albumin...

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Detalles Bibliográficos
Autores principales: Wakefield, Devin L., Holowka, David, Baird, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687038/
https://www.ncbi.nlm.nih.gov/pubmed/28794269
http://dx.doi.org/10.1091/mbc.E17-03-0208