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Homologated amino acids with three vicinal fluorines positioned along the backbone: development of a stereoselective synthesis
Backbone-extended amino acids have a variety of potential applications in peptide and protein science, particularly if the geometry of the amino acid is controllable. Here we describe the synthesis of δ-amino acids that contain three vicinal C–F bonds positioned along the backbone. The ultimately su...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687047/ https://www.ncbi.nlm.nih.gov/pubmed/29181111 http://dx.doi.org/10.3762/bjoc.13.228 |