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Restoration of KLF4 Inhibits Invasion and Metastases of Lung Adenocarcinoma through Suppressing MMP2

Background: KLF4 is a zin-finger transcription factor that plays roles in differentiation, development, and proliferation. Recent studies show that KLF4 is involved in tumorigenesis and somatic cells reprogramming. Metastasis is the primary cause of death in patients with lung cancer, and its biolog...

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Detalles Bibliográficos
Autores principales: Li, Shaoli, Huang, Lixia, Gu, Jincui, Wu, Jian, Ou, Weijun, Feng, Jinglun, Liu, Baomo, Cui, Xiaoxian, Zhou, Yanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687162/
https://www.ncbi.nlm.nih.gov/pubmed/29151932
http://dx.doi.org/10.7150/jca.21241