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An improved LC-MS/MS method for the quantification of alverine and para hydroxy alverine in human plasma for a bioequivalence study(☆)()

A highly sensitive and selective high performance liquid chromatography-tandem mass spectrometry method was developed and validated for the quantification of alverine (ALV) and its active metabolite, para hydroxy alverine (PHA), in human plasma. For sample preparation, solid phase extraction of anal...

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Detalles Bibliográficos
Autores principales: Rathod, Dhiraj M., Patel, Keyur R., Mistri, Hiren N., Jangid, Arvind G., Shrivastav, Pranav S., Sanyal, Mallika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687197/
https://www.ncbi.nlm.nih.gov/pubmed/29404023
http://dx.doi.org/10.1016/j.jpha.2016.11.003