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Two independent modes of chromatin organization revealed by cohesin removal

Imaging and chromosome conformation capture studies have revealed several layers of chromosome organization, including segregation into megabase-large active and inactive compartments, and partitioning into sub-megabase domains (TADs). Yet, it remains unclear how these layers of organization form, i...

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Detalles Bibliográficos
Autores principales: Schwarzer, Wibke, Abdennur, Nezar, Goloborodko, Anton, Pekowska, Aleksandra, Fudenberg, Geoffrey, Loe-Mie, Yann, Fonseca, Nuno A, Huber, Wolfgang, Haering, Christian, Mirny, Leonid, Spitz, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687303/
https://www.ncbi.nlm.nih.gov/pubmed/29094699
http://dx.doi.org/10.1038/nature24281