Cargando…
Two independent modes of chromatin organization revealed by cohesin removal
Imaging and chromosome conformation capture studies have revealed several layers of chromosome organization, including segregation into megabase-large active and inactive compartments, and partitioning into sub-megabase domains (TADs). Yet, it remains unclear how these layers of organization form, i...
Autores principales: | Schwarzer, Wibke, Abdennur, Nezar, Goloborodko, Anton, Pekowska, Aleksandra, Fudenberg, Geoffrey, Loe-Mie, Yann, Fonseca, Nuno A, Huber, Wolfgang, Haering, Christian, Mirny, Leonid, Spitz, Francois |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687303/ https://www.ncbi.nlm.nih.gov/pubmed/29094699 http://dx.doi.org/10.1038/nature24281 |
Ejemplares similares
-
Emerging Evidence of Chromosome Folding by Loop Extrusion
por: Fudenberg, Geoffrey, et al.
Publicado: (2018) -
Chromatin organization by an interplay of loop extrusion and compartmental segregation
por: Nuebler, Johannes, et al.
Publicado: (2018) -
Pairtools: from sequencing data to chromosome contacts
por: Abdennur, Nezar, et al.
Publicado: (2023) -
Diverse silent chromatin states modulate genome compartmentalization and loop extrusion barriers
por: Spracklin, George, et al.
Publicado: (2022) -
Chromatin Loops as Allosteric Modulators of Enhancer-Promoter Interactions
por: Doyle, Boryana, et al.
Publicado: (2014)