Integrative epigenetic and genetic pan-cancer somatic alteration portraits

Genetic and epigenetic alterations are required for carcinogenesis and the mutation burden across tumor types has been investigated. Here, we investigate epigenetic alterations with a novel measure of global DNA methylation dysregulation, the methylation dysregulation index (MDI), across 14 cancer t...

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Detalles Bibliográficos
Autores principales: Salas, Lucas A., Johnson, Kevin C., Koestler, Devin C., O'Sullivan, Dylan E., Christensen, Brock C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687331/
https://www.ncbi.nlm.nih.gov/pubmed/28426276
http://dx.doi.org/10.1080/15592294.2017.1319043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687331/
https://www.ncbi.nlm.nih.gov/pubmed/28426276
http://dx.doi.org/10.1080/15592294.2017.1319043

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