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Integrative epigenetic and genetic pan-cancer somatic alteration portraits

Genetic and epigenetic alterations are required for carcinogenesis and the mutation burden across tumor types has been investigated. Here, we investigate epigenetic alterations with a novel measure of global DNA methylation dysregulation, the methylation dysregulation index (MDI), across 14 cancer t...

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Detalles Bibliográficos
Autores principales:	Salas, Lucas A., Johnson, Kevin C., Koestler, Devin C., O'Sullivan, Dylan E., Christensen, Brock C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687331/ https://www.ncbi.nlm.nih.gov/pubmed/28426276 http://dx.doi.org/10.1080/15592294.2017.1319043

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