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Genome-wide 5-hydroxymethylcytosine patterns in human spermatogenesis are associated with semen quality

We performed immunofluorescent analysis of DNA hydroxymethylation and methylation in human testicular spermatogenic cells from azoospermic patients and ejaculated spermatozoa from sperm donors and patients from infertile couples. In contrast to methylation which was present throughout spermatogenesi...

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Detalles Bibliográficos
Autores principales: Efimova, Olga A., Pendina, Anna A., Tikhonov, Andrei V., Parfenyev, Sergey E., Mekina, Irina D., Komarova, Evgeniia M., Mazilina, Mariia A., Daev, Eugene V., Chiryaeva, Olga G., Galembo, Ilona A., Krapivin, Mikhail I., Glotov, Oleg S., Stepanova, Irina S., Shlykova, Svetlana A., Kogan, Igor Yu., Gzgzyan, Alexander M., Kuznetzova, Tatyana V., Baranov, Vladislav S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687605/
https://www.ncbi.nlm.nih.gov/pubmed/29179435
http://dx.doi.org/10.18632/oncotarget.18331