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Shikonin reduces tamoxifen resistance through long non-coding RNA uc.57

Tamoxifen resistance is a serious problem in the endocrine therapy of breast cancer. Long non-coding RNAs play important roles in tumor development. In this study, we revealed the involvement of lncRNA uc.57 and its downstream gene BCL11A in TAM resistance. Tamoxifen-resistant MCF-7R cells showed lo...

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Detalles Bibliográficos
Autores principales: Zhang, Chen-Han, Wang, Jue, Zhang, Lin-Xin, Lu, Yi-Han, Ji, Tian-Hao, Xu, Lu, Ling, Li-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687635/
https://www.ncbi.nlm.nih.gov/pubmed/29179465
http://dx.doi.org/10.18632/oncotarget.20809