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Anti-angiogenic drugs: direct anti-cancer agents with mitochondrial mechanisms of action

Components of the mitochondrial electron transport chain have recently gained much interest as potential therapeutic targets. Since mitochondria are essential for the supply of energy that is required for both angiogenic and tumourigenic activity, targeting the mitochondria represents a promising po...

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Detalles Bibliográficos
Autores principales: Quayle, Lewis A., Pereira, Maria G., Scheper, Gerjan, Wiltshire, Tammy, Peake, Ria E., Hussain, Issam, Rea, Carol A., Bates, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687636/
https://www.ncbi.nlm.nih.gov/pubmed/29179466
http://dx.doi.org/10.18632/oncotarget.20858