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Histone deacetylase 6 inhibition counteracts the epithelial–mesenchymal transition of peritoneal mesothelial cells and prevents peritoneal fibrosis

The role of histone deacetylase 6 (HDAC6) in peritoneal fibrosis remains unknown. In this study, we examined the effect of HDAC6 inhibition on the epithelial–mesenchymal transition (EMT) of peritoneal mesothelial cells and development of peritoneal fibrosis. Treatment with tubastatin A, a highly sel...

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Detalles Bibliográficos
Autores principales: Xu, Liuqing, Liu, Na, Gu, Hongwei, Wang, Hongrui, Shi, Yingfeng, Ma, Xiaoyan, Ma, Shuchen, Ni, Jun, Tao, Min, Qiu, Andong, Zhuang, Shougang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687641/
https://www.ncbi.nlm.nih.gov/pubmed/29179471
http://dx.doi.org/10.18632/oncotarget.20982