Cargando…

Splenectomy is associated with an aggressive tumor growth pattern and altered host immunity in an orthotopic syngeneic murine pancreatic cancer model

The purpose of this study was to investigate whether splenectomy influences the tumor growth and metastatic pattern in an orthotopic syngeneic murine pancreatic cancer model. Murine pancreatic cancer cells (PAN02) were subcutaneously injected into the flanks of nude mice. A small tumor fragment (3 m...

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, Ho Kyoung, Murakami, Takashi, Kiyuna, Tasuku, Kim, Se Hoon, Lee, Sung Hwan, Kang, Chang Moo, Hoffman, Robert M., Bouvet, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687649/
https://www.ncbi.nlm.nih.gov/pubmed/29179479
http://dx.doi.org/10.18632/oncotarget.21331