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Splenectomy is associated with an aggressive tumor growth pattern and altered host immunity in an orthotopic syngeneic murine pancreatic cancer model
The purpose of this study was to investigate whether splenectomy influences the tumor growth and metastatic pattern in an orthotopic syngeneic murine pancreatic cancer model. Murine pancreatic cancer cells (PAN02) were subcutaneously injected into the flanks of nude mice. A small tumor fragment (3 m...
Autores principales: | Hwang, Ho Kyoung, Murakami, Takashi, Kiyuna, Tasuku, Kim, Se Hoon, Lee, Sung Hwan, Kang, Chang Moo, Hoffman, Robert M., Bouvet, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687649/ https://www.ncbi.nlm.nih.gov/pubmed/29179479 http://dx.doi.org/10.18632/oncotarget.21331 |
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