Functional expression of Tim-3 on blasts and clinical impact of its ligand galectin-9 in myelodysplastic syndromes

T-cell immunoglobulin mucin-3 (Tim-3), an inhibitory immune checkpoint receptor, is highly expressed on acute myeloid leukemia cells and its ligand galectin-9 is reported to drive leukemic progression by binding with Tim-3. However, it remains unclear whether the Tim-3–galectin-9 pathway is associat...

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Detalles Bibliográficos
Autores principales: Asayama, Toshio, Tamura, Hideto, Ishibashi, Mariko, Kuribayashi-Hamada, Yasuko, Onodera-Kondo, Asaka, Okuyama, Namiko, Yamada, Akiko, Shimizu, Masumi, Moriya, Keiichi, Takahashi, Hidemi, Inokuchi, Koiti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687656/
https://www.ncbi.nlm.nih.gov/pubmed/29179486
http://dx.doi.org/10.18632/oncotarget.21492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687656/
https://www.ncbi.nlm.nih.gov/pubmed/29179486
http://dx.doi.org/10.18632/oncotarget.21492

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