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SIRT1 promotes tumor-like invasion of fibroblast-like synoviocytes in rheumatoid arthritis via targeting TIMP1

Suppression of tissue inhibitor of matrix metalloproteinase (TIMP) is associated with the tumor-like invasion of fibroblast-like synoviocytes (FLSs) that occurs during rheumatoid arthritis-related cartilage destruction. Silent information regulator 2 homolog1 (SIRT1), a histone deacetylase, is widel...

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Detalles Bibliográficos
Autores principales: Guo, Jiangtao, Zhao, Wei, Cao, Xuqing, Yang, Huiying, Ding, Juan, Ding, Jingbin, Tan, Zifang, Ma, Xiaoli, Hao, Chunfang, Wu, Lili, Ma, Zhengjuan, Xie, Jianjun, Wang, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687661/
https://www.ncbi.nlm.nih.gov/pubmed/29179491
http://dx.doi.org/10.18632/oncotarget.21628