Childhood tuberculosis is associated with decreased abundance of T cell gene transcripts and impaired T cell function

The WHO estimates around a million children contract tuberculosis (TB) annually with over 80 000 deaths from dissemination of infection outside of the lungs. The insidious onset and association with skin test anergy suggests failure of the immune system to both recognise and respond to infection. To...

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Detalles Bibliográficos
Autores principales: Hemingway, Cheryl, Berk, Maurice, Anderson, Suzanne T., Wright, Victoria J., Hamilton, Shea, Eleftherohorinou, Hariklia, Kaforou, Myrsini, Goldgof, Greg M., Hickman, Katy, Kampmann, Beate, Schoeman, Johan, Eley, Brian, Beatty, David, Pienaar, Sandra, Nicol, Mark P., Griffiths, Michael J., Waddell, Simon J., Newton, Sandra M., Coin, Lachlan J., Relman, David A., Montana, Giovanni, Levin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687722/
https://www.ncbi.nlm.nih.gov/pubmed/29140996
http://dx.doi.org/10.1371/journal.pone.0185973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687722/
https://www.ncbi.nlm.nih.gov/pubmed/29140996
http://dx.doi.org/10.1371/journal.pone.0185973

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