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Prognostic significance of cyclin D1 protein expression and gene amplification in invasive breast carcinoma

The oncogenic capacity of cyclin D1 has long been established in breast cancer. CCND1 amplification has been identified in a subset of patients with poor prognosis, but there are conflicting data regarding the predictive value of cyclin D1 protein overexpression. This study was designed to analyze t...

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Detalles Bibliográficos
Autores principales: Ortiz, Angela B., Garcia, Diego, Vicente, Yolanda, Palka, Magda, Bellas, Carmen, Martin, Paloma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687747/
https://www.ncbi.nlm.nih.gov/pubmed/29140993
http://dx.doi.org/10.1371/journal.pone.0188068