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Notch signaling and progenitor/ductular reaction in steatohepatitis

BACKGROUND AND OBJECTIVE: Persistent hepatic progenitor cells (HPC) activation resulting in ductular reaction (DR) is responsible for pathologic liver repair in cholangiopathies. Also, HPC/DR expansion correlates with fibrosis in several chronic liver diseases, including steatohepatitis. Increasing...

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Detalles Bibliográficos
Autores principales: Morell, Carola M., Fiorotto, Romina, Meroni, Marica, Raizner, Aileen, Torsello, Barbara, Cadamuro, Massimiliano, Spagnuolo, Gaia, Kaffe, Eleanna, Sutti, Salvatore, Albano, Emanuele, Strazzabosco, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687773/
https://www.ncbi.nlm.nih.gov/pubmed/29140985
http://dx.doi.org/10.1371/journal.pone.0187384