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Hypercholesterolemia Enhances T Cell Receptor Signaling and Increases the Regulatory T Cell Population

Hypercholesterolemia promotes the inflammation against lipoproteins in atherosclerosis. Development of atherosclerosis is affected by the balance between pro-inflammatory effector T cells and anti-inflammatory regulatory T (Treg) cells. However, phenotype and function of T cell subpopulations in hyp...

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Detalles Bibliográficos
Autores principales: Mailer, Reiner K. W., Gisterå, Anton, Polyzos, Konstantinos A., Ketelhuth, Daniel F. J., Hansson, Göran K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688061/
https://www.ncbi.nlm.nih.gov/pubmed/29142309
http://dx.doi.org/10.1038/s41598-017-15546-8