FUS toxicity is rescued by the modulation of lncRNA hsrω expression in Drosophila melanogaster

FUS is an aggregation-prone hnRNP involved in transcriptional and post-transcriptional regulation that aberrantly forms immunoreactive inclusion bodies in a range of neurological diseases classified as FUS-proteinopathies. Although FUS has been extensively examined, the underlying molecular mechanis...

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Detalles Bibliográficos
Autores principales: Lo Piccolo, Luca, Jantrapirom, Salinee, Nagai, Yoshitaka, Yamaguchi, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688078/
https://www.ncbi.nlm.nih.gov/pubmed/29142303
http://dx.doi.org/10.1038/s41598-017-15944-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688078/
https://www.ncbi.nlm.nih.gov/pubmed/29142303
http://dx.doi.org/10.1038/s41598-017-15944-y

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