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FUS toxicity is rescued by the modulation of lncRNA hsrω expression in Drosophila melanogaster
FUS is an aggregation-prone hnRNP involved in transcriptional and post-transcriptional regulation that aberrantly forms immunoreactive inclusion bodies in a range of neurological diseases classified as FUS-proteinopathies. Although FUS has been extensively examined, the underlying molecular mechanis...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688078/ https://www.ncbi.nlm.nih.gov/pubmed/29142303 http://dx.doi.org/10.1038/s41598-017-15944-y |