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Hyperspectral Raman imaging of neuritic plaques and neurofibrillary tangles in brain tissue from Alzheimer’s disease patients

Neuritic plaques and neurofibrillary tangles are crucial morphological criteria for the definite diagnosis of Alzheimer’s disease. We evaluated 12 unstained frontal cortex and hippocampus samples from 3 brain donors with Alzheimer’s disease and 1 control with hyperspectral Raman microscopy on sample...

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Detalles Bibliográficos
Autores principales: Michael, Ralph, Lenferink, Aufried, Vrensen, Gijs F. J. M., Gelpi, Ellen, Barraquer, Rafael I., Otto, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688091/
https://www.ncbi.nlm.nih.gov/pubmed/29142266
http://dx.doi.org/10.1038/s41598-017-16002-3