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Hyperspectral Raman imaging of neuritic plaques and neurofibrillary tangles in brain tissue from Alzheimer’s disease patients
Neuritic plaques and neurofibrillary tangles are crucial morphological criteria for the definite diagnosis of Alzheimer’s disease. We evaluated 12 unstained frontal cortex and hippocampus samples from 3 brain donors with Alzheimer’s disease and 1 control with hyperspectral Raman microscopy on sample...
Autores principales: | Michael, Ralph, Lenferink, Aufried, Vrensen, Gijs F. J. M., Gelpi, Ellen, Barraquer, Rafael I., Otto, Cees |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688091/ https://www.ncbi.nlm.nih.gov/pubmed/29142266 http://dx.doi.org/10.1038/s41598-017-16002-3 |
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