Cargando…

Structural basis for tRNA-dependent cysteine biosynthesis

Cysteine can be synthesized by tRNA-dependent mechanism using a two-step indirect pathway, where O-phosphoseryl-tRNA synthetase (SepRS) catalyzes the ligation of a mismatching O-phosphoserine (Sep) to tRNA(Cys) followed by the conversion of tRNA-bounded Sep into cysteine by Sep-tRNA:Cys-tRNA synthas...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Meirong, Kato, Koji, Kubo, Yume, Tanaka, Yoshikazu, Liu, Yuchen, Long, Feng, Whitman, William B., Lill, Pascal, Gatsogiannis, Christos, Raunser, Stefan, Shimizu, Nobutaka, Shinoda, Akira, Nakamura, Akiyoshi, Tanaka, Isao, Yao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688128/
https://www.ncbi.nlm.nih.gov/pubmed/29142195
http://dx.doi.org/10.1038/s41467-017-01543-y