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Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis

Spondyloarthritis encompasses a group of common inflammatory diseases thought to be driven by IL-17A-secreting type-17 lymphocytes. Here we show increased numbers of GM-CSF-producing CD4 and CD8 lymphocytes in the blood and joints of patients with spondyloarthritis, and increased numbers of IL-17A(+...

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Detalles Bibliográficos
Autores principales: Al-Mossawi, M. H., Chen, L., Fang, H., Ridley, A., de Wit, J., Yager, N., Hammitzsch, A., Pulyakhina, I., Fairfax, B. P., Simone, D., Yi, Yao, Bandyopadhyay, S., Doig, K., Gundle, R, Kendrick, B., Powrie, F., Knight, J. C., Bowness, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688161/
https://www.ncbi.nlm.nih.gov/pubmed/29142230
http://dx.doi.org/10.1038/s41467-017-01771-2