Human ATG3 binding to lipid bilayers: role of lipid geometry, and electric charge

Specific protein-lipid interactions lead to a gradual recruitment of AuTophaGy-related (ATG) proteins to the nascent membrane during autophagosome (AP) formation. ATG3, a key protein in the movement of LC3 towards the isolation membrane, has been proposed to facilitate LC3/GABARAP lipidation in high...

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Detalles Bibliográficos
Autores principales: Hervás, Javier H., Landajuela, Ane, Antón, Zuriñe, Shnyrova, Anna V., Goñi, Felix M., Alonso, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688168/
https://www.ncbi.nlm.nih.gov/pubmed/29142222
http://dx.doi.org/10.1038/s41598-017-15057-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688168/
https://www.ncbi.nlm.nih.gov/pubmed/29142222
http://dx.doi.org/10.1038/s41598-017-15057-6

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