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Human ATG3 binding to lipid bilayers: role of lipid geometry, and electric charge
Specific protein-lipid interactions lead to a gradual recruitment of AuTophaGy-related (ATG) proteins to the nascent membrane during autophagosome (AP) formation. ATG3, a key protein in the movement of LC3 towards the isolation membrane, has been proposed to facilitate LC3/GABARAP lipidation in high...
Autores principales: | Hervás, Javier H., Landajuela, Ane, Antón, Zuriñe, Shnyrova, Anna V., Goñi, Felix M., Alonso, Alicia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688168/ https://www.ncbi.nlm.nih.gov/pubmed/29142222 http://dx.doi.org/10.1038/s41598-017-15057-6 |
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