The PRDM9 KRAB domain is required for meiosis and involved in protein interactions

PR domain-containing protein 9 (PRDM9) is a major regulator of the localization of meiotic recombination hotspots in the human and mouse genomes. This role involves its DNA-binding domain, which is composed of a tandem array of zinc fingers, and PRDM9-dependent trimethylation of histone H3 at lysine...

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Detalles Bibliográficos
Autores principales: Imai, Yukiko, Baudat, Frédéric, Taillepierre, Miguel, Stanzione, Marcello, Toth, Attila, de Massy, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688218/
https://www.ncbi.nlm.nih.gov/pubmed/28527011
http://dx.doi.org/10.1007/s00412-017-0631-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688218/
https://www.ncbi.nlm.nih.gov/pubmed/28527011
http://dx.doi.org/10.1007/s00412-017-0631-z

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