Cargando…

FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by Repressing Jagged1 Expression

Mutations in FOXP1 have been linked to neurodevelopmental disorders including intellectual disability and autism; however, the underlying molecular mechanisms remain ill-defined. Here, we demonstrate with RNA and chromatin immunoprecipitation sequencing that FOXP1 directly regulates genes controllin...

Descripción completa

Detalles Bibliográficos
Autores principales: Braccioli, Luca, Vervoort, Stephin J., Adolfs, Youri, Heijnen, Cobi J., Basak, Onur, Pasterkamp, R. Jeroen, Nijboer, Cora H., Coffer, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688236/
https://www.ncbi.nlm.nih.gov/pubmed/29141232
http://dx.doi.org/10.1016/j.stemcr.2017.10.012