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FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by Repressing Jagged1 Expression
Mutations in FOXP1 have been linked to neurodevelopmental disorders including intellectual disability and autism; however, the underlying molecular mechanisms remain ill-defined. Here, we demonstrate with RNA and chromatin immunoprecipitation sequencing that FOXP1 directly regulates genes controllin...
Autores principales: | Braccioli, Luca, Vervoort, Stephin J., Adolfs, Youri, Heijnen, Cobi J., Basak, Onur, Pasterkamp, R. Jeroen, Nijboer, Cora H., Coffer, Paul J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688236/ https://www.ncbi.nlm.nih.gov/pubmed/29141232 http://dx.doi.org/10.1016/j.stemcr.2017.10.012 |
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