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A statistical approach for evaluating the effectiveness of heartworm preventive drugs: what does 100% efficacy really mean?

BACKGROUND: Initial studies of heartworm preventive drugs all yielded an observed efficacy of 100% with a single dose, and based on these data the US Food and Drug Administration (FDA) required all products to meet this standard for approval. Those initial studies, however, were based on just a few...

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Detalles Bibliográficos
Autores principales: Vidyashankar, Anand N., Jimenez Castro, Pablo D., Kaplan, Ray M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688406/
https://www.ncbi.nlm.nih.gov/pubmed/29143648
http://dx.doi.org/10.1186/s13071-017-2440-x