Proteotoxic Stress Desensitizes TGF-beta Signaling Through Receptor Downregulation in Retinal Pigment Epithelial Cells

BACKGROUND: Proteotoxic stress and transforming growth factor (TGFβ)-induced epithelial-mesenchymal transition (EMT) are two main contributors of intraocular fibrotic disorders, including proliferative vitreoretinopathy (PVR) and proliferative diabetic retinopathy (PDR). However, how these two facto...

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Detalles Bibliográficos
Autores principales: Tan, X., Chen, C., Zhu, Y., Deng, J., Qiu, X., Huang, S., Shang, F., Cheng, B., Liu, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688417/
https://www.ncbi.nlm.nih.gov/pubmed/28625142
http://dx.doi.org/10.2174/1566524017666170619113435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688417/
https://www.ncbi.nlm.nih.gov/pubmed/28625142
http://dx.doi.org/10.2174/1566524017666170619113435

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