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Does evaluation of in vitro microfilarial motility reflect the resistance status of Dirofilaria immitis isolates to macrocyclic lactones?

BACKGROUND: Several reports have confirmed that macrocyclic lactone-resistant isolates of Dirofilaria immitis are circulating in the United States; however, the prevalence and potential impact of drug resistance is unknown. We wished to assess computer-aided measurements of motility as a method for...

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Detalles Bibliográficos
Autores principales: Maclean, Mary J., Savadelis, Molly D., Coates, Ruby, Dzimianski, Michael T., Jones, Corey, Benbow, Cynthia, Storey, Bobby E., Kaplan, Ray M., Moorhead, Andrew R., Wolstenholme, Adrian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688452/
https://www.ncbi.nlm.nih.gov/pubmed/29143656
http://dx.doi.org/10.1186/s13071-017-2436-6