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Bioinformatics prediction of miR-30a targets and its inhibition of cell proliferation of osteosarcoma by up-regulating the expression of PTEN

BACKGROUND: MiRNAs are frequently abnormally expressed in the progression of human osteosarcoma. Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is one of the tumor suppressors in various types of human cancer. In the present study, we detected how hsa-miR-30a-3p regulated PTEN and...

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Detalles Bibliográficos
Autores principales: Zhong, Biao, Guo, Shang, Zhang, Wei, Zhang, Chi, Wang, Yukai, Zhang, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688649/
https://www.ncbi.nlm.nih.gov/pubmed/29141684
http://dx.doi.org/10.1186/s12920-017-0300-3