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Inhibiting the microglia activation improves the spatial memory and adult neurogenesis in rat hippocampus during 48 h of sleep deprivation

BACKGROUND: Sleep deprivation (SD) leads to cognitive impairment. Neuroinflammation could be a significant contributing factor in the same. An increase in regional brain pro-inflammatory cytokines induces cognitive deficits, however, the magnitude of the effect under SD is not apparent. It is plausi...

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Detalles Bibliográficos
Autores principales: Wadhwa, Meetu, Prabhakar, Amit, Ray, Koushik, Roy, Koustav, Kumari, Punita, Jha, Prabhash Kumar, Kishore, Krishna, Kumar, Sanjeev, Panjwani, Usha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688670/
https://www.ncbi.nlm.nih.gov/pubmed/29141671
http://dx.doi.org/10.1186/s12974-017-0998-z