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miR-200b downregulates CFTR during hypoxia in human lung epithelial cells

BACKGROUND: Hypoxic conditions induce the expression of hypoxia-inducible factors (HIFs) that allow cells to adapt to the changing conditions and alter the expression of a number of genes including the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is a low abundance mRNA in airway...

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Detalles Bibliográficos
Autores principales: Bartoszewska, Sylwia, Kamysz, Wojciech, Jakiela, Bogdan, Sanak, Marek, Króliczewski, Jarosław, Bebok, Zsuzsa, Bartoszewski, Rafal, Collawn, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688675/
https://www.ncbi.nlm.nih.gov/pubmed/29167681
http://dx.doi.org/10.1186/s11658-017-0054-0