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miR-200b downregulates CFTR during hypoxia in human lung epithelial cells
BACKGROUND: Hypoxic conditions induce the expression of hypoxia-inducible factors (HIFs) that allow cells to adapt to the changing conditions and alter the expression of a number of genes including the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is a low abundance mRNA in airway...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688675/ https://www.ncbi.nlm.nih.gov/pubmed/29167681 http://dx.doi.org/10.1186/s11658-017-0054-0 |