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Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain: 1-year follow-up of a phase I study

BACKGROUND: Adipose tissue-derived mesenchymal stem cells (AT-MSCs) offer potential as a therapeutic option for chronic discogenic low back pain (LBP) because of their immunomodulatory functions and capacity for cartilage differentiation. The goal of this study was to assess the safety and tolerabil...

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Detalles Bibliográficos
Autores principales: Kumar, Hemant, Ha, Doo-Hoe, Lee, Eun-Jong, Park, Jun Hee, Shim, Jeong Hyun, Ahn, Tae-Keun, Kim, Kyoung-Tae, Ropper, Alexander E., Sohn, Seil, Kim, Chung-Hun, Thakor, Devang Kashyap, Lee, Soo-Hong, Han, In-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688755/
https://www.ncbi.nlm.nih.gov/pubmed/29141662
http://dx.doi.org/10.1186/s13287-017-0710-3