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Local estrogen axis in the human bone microenvironment regulates estrogen receptor-positive breast cancer cells

BACKGROUND: Approximately 70% of all breast cancers express the estrogen receptor, and are regulated by estrogen. While the ovaries are the primary source of estrogen in premenopausal women, most breast cancer is diagnosed following menopause, when systemic levels of this hormone decline. Estrogen p...

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Detalles Bibliográficos
Autores principales: Amanatullah, Derek F., Tamaresis, John S., Chu, Pauline, Bachmann, Michael H., Hoang, Nhat M., Collyar, Deborah, Mayer, Aaron T., West, Robert B., Maloney, William J., Contag, Christopher H., King, Bonnie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688761/
https://www.ncbi.nlm.nih.gov/pubmed/29141657
http://dx.doi.org/10.1186/s13058-017-0910-x