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Reconstructing cancer karyotypes from short read data: the half empty and half full glass
BACKGROUND: During cancer progression genomes undergo point mutations as well as larger segmental changes. The latter include, among others, segmental deletions duplications, translocations and inversions.The result is a highly complex, patient-specific cancer karyotype. Using high-throughput techno...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688766/ https://www.ncbi.nlm.nih.gov/pubmed/29141589 http://dx.doi.org/10.1186/s12859-017-1929-9 |