MiR‐335 overexpression impairs insulin secretion through defective priming of insulin vesicles

MicroRNAs contribute to the maintenance of optimal cellular functions by fine‐tuning protein expression levels. In the pancreatic β‐cells, imbalances in the exocytotic machinery components lead to impaired insulin secretion and type 2 diabetes (T2D). We hypothesize that dysregulated miRNA expression...

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Detalles Bibliográficos
Autores principales: Salunkhe, Vishal A., Ofori, Jones K., Gandasi, Nikhil R., Salö, Sofia A., Hansson, Sofia, Andersson, Markus E., Wendt, Anna, Barg, Sebastian, Esguerra, Jonathan L. S., Eliasson, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688784/
https://www.ncbi.nlm.nih.gov/pubmed/29122960
http://dx.doi.org/10.14814/phy2.13493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688784/
https://www.ncbi.nlm.nih.gov/pubmed/29122960
http://dx.doi.org/10.14814/phy2.13493

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